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Fig. 5 | Cancer Cell International

Fig. 5

From: Knockdown of RSPH14 inhibits proliferation, migration, and invasion and promotes apoptosis of hepatocellular carcinoma via RelA

Fig. 5

RSPH14 knockdown inhibited the proliferation and migration of HCC cell lines by suppressing RelA expression. A Western blot analysis. B HCS assay. C MTT assay. D Transwell migratory assay. The images were scanned at ×100 magnification. All experiments were performed three times. NC + NC: negative control + negative control; KD + NC: RSPH14 knockdown + negative control; KD + AKT1: RSPH14 knockdown + AKT1 overexpression; KD + CDH2: RSPH14 knockdown + CDH2 overexpression; KD + RelA: RSPH14 knockdown + RelA overexpression; HCC: hepatocellular carcinoma; HCS: high-content screening. *P < 0.05, **P < 0.01, ***P < 0.001

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