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Fig. 7 | Cancer Cell International

Fig. 7

From: AMICA1 is a diagnostic and prognostic biomarker and induces immune cells infiltration by activating cGAS-STING signaling in lung adenocarcinoma

Fig. 7

Overexpression of AMICA1 activated cGAS-STING signaling and promoted expression of type I interferon. A The correlation between AMICA1 and cGAS-STING signaling mRNA in LUAD tissues. B, C Over expression of AMICA1 promoted the expression of TMEM173 mRNA. D and F Over expression of AMICA1 promoted the expression of TMEM173 protein. E and G Over expression of AMICA1 activated cGAS-STING signaling and promoted expression of type I interferon. H, I Immunofluorescence staining of TMEM173 in A549 and H1437 cells. J AMICA1 had no influence in the location of TMEM173

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