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Fig. 1 | Cancer Cell International

Fig. 1

From: HOXA7 promotes the metastasis of KRAS mutant colorectal cancer by regulating myeloid-derived suppressor cells

Fig. 1

Elevated HOXA7 expression is positively correlated with poor prognosis in KRAS mutant CRC. A Relative HOXA7 mRNA expression in 20 normal colon tissues and 100 paired CRC and adjacent nontumorous tissues (left). Relative HOXA7 mRNA expression in CRC tissues expressing wild-type KRAS or mutant KRAS (right). B Western blotting analysis of HOXA7 expression in KRAS mutant CRC cell lines (SW620, HCT116, and LOVO) and KRAS wild-type CRC cell lines (HT29, Caco-2, HCA-7). C Representative IHC images of HOXA7 expression in paired adjacent nontumor tissues, primary CRC tissues, and metastatic CRC tissues. D Representative IHC images of HOXA7 expression in KRAS wild-type CRC (left) and KRAS mutant CRC (right). E The rate of high HOXA7 expression, low HOXA7 expression and negative HOXA7 expression in KRAS wild-type CRC and KRAS mutant CRC. F Kaplan–Meier analysis of the correlation of HOXA7 expression with overall survival in the human CRC cohort (left), KRAS wild-type CRC (middle), and KRAS mutant CRC (right)

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Cancer Cell International

ISSN: 1475-2867

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