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Table 2 Univariate and multivariate analysis of factors associated with survival and recurrence in a cohort of human CRC (overall population)

From: HOXA7 promotes the metastasis of KRAS mutant colorectal cancer by regulating myeloid-derived suppressor cells

Clinical variables Univariate COX regression analysis Multivariate COX regression analysis
HR (95% CI) P value HR (95% CI) P value
Age (≤ 50 vs > 50) 1.065 (0.750–1.512) 0.726   
Gender (female vs male) 1.142 (0.885–686) 0.349   
Tumor size (≤ 5 cm vs > 5 cm) 1.278 (0.985–1.658) 0.065   
Tumor differentiation (well/moderate vs poor) 0.185 (0.141–0.242) < 0.001 0.733 (0.522–1.030) 0.073
Tumor invasion (I–II vs III) 0.234 (0.262–0.455) < 0.001 0.570 (0.420–0.774) < 0.001
Lymph node metastasis (absent vs present) 0.122 (0.070–0.132) < 0.001 0.560 (0.313–1.002) 0.051
Distant metastasis (absent vs present) 0.155 (0.114–0.211) < 0.001 0.508 (0.351–0.737) < 0.001
TNM stage (I/II vs III/IV) 0.096 (0.114–0.211) < 0.001 0.232 (0.131–0.412) < 0.001
HOXA7 expression (negative vs positive) 0.418 (0.322–0.541) < 0.001 0.724 (0.552–0.948) 0.019