Table 2 Univariate and multivariate analysis of factors associated with survival and recurrence in a cohort of human CRC (overall population)
Clinical variables | Univariate COX regression analysis | Multivariate COX regression analysis | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age (≤ 50 vs > 50) | 1.065 (0.750–1.512) | 0.726 | ||
Gender (female vs male) | 1.142 (0.885–686) | 0.349 | ||
Tumor size (≤ 5 cm vs > 5 cm) | 1.278 (0.985–1.658) | 0.065 | ||
Tumor differentiation (well/moderate vs poor) | 0.185 (0.141–0.242) | < 0.001 | 0.733 (0.522–1.030) | 0.073 |
Tumor invasion (I–II vs III) | 0.234 (0.262–0.455) | < 0.001 | 0.570 (0.420–0.774) | < 0.001 |
Lymph node metastasis (absent vs present) | 0.122 (0.070–0.132) | < 0.001 | 0.560 (0.313–1.002) | 0.051 |
Distant metastasis (absent vs present) | 0.155 (0.114–0.211) | < 0.001 | 0.508 (0.351–0.737) | < 0.001 |
TNM stage (I/II vs III/IV) | 0.096 (0.114–0.211) | < 0.001 | 0.232 (0.131–0.412) | < 0.001 |
HOXA7 expression (negative vs positive) | 0.418 (0.322–0.541) | < 0.001 | 0.724 (0.552–0.948) | 0.019 |