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Fig. 3 | Cancer Cell International

Fig. 3

From: Identification of proteomic markers for prediction of the response to 5-Fluorouracil based neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

Fig. 3

Validation of the proteins associated with 5-FU-based nCRT resisitance. a–c The gene expression in the external validation cohort (n = 56) is shown as scatter plots. Statistical significance between responders and non-responders was calculated using the Mann–Whitney test. d–f The relationship between the individual protein level of HSPA4, NIPSNAP1, and SPTB, as well as the therapeutic response grades in the total internal cohort (n = 37), are shown as scatter plots. P-values for trends were calculated using the one-way ANOVA post-test for linear trends. TR, total responders; MR, moderate responders; PR, poor responders. (*p < 0.05; **p < 0.01 and ***p < 0.001)

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Cancer Cell International

ISSN: 1475-2867

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