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Table 2 Associations of pathological characteristics with different responses to nCRT

From: Identification of proteomic markers for prediction of the response to 5-Fluorouracil based neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

Pathological characteristics

 

All

TR

PR

p

n

 

20

9

11

 

Histological classification (biopsy), n (%)

Moderately differentiated

19 (95.0)

8 (88.9)

11 (100.0)

0.450

 

Not available

1 (5.0)

1 (11.1)

0 (0.0)

 

Mucinous classification, n (%)

Non-mucinous

19 (95.0)

8 (88.9)

11 (100.0)

0.450

 

Mucinous

1 (5.0)

1 (11.1)

0 (0.0)

 

Neurovascular invasion, n (%)

 

2 (10.0)

0 (0.0)

2 (18.2)

0.479

ypStage, n (%)

pCR

9 (45.0)

9 (100.0)

0 (0.0)

0.000

 

I

2 (10.0)

0 (0.0)

2 (18.2)

 
 

II

6 (30.0)

0 (0.0)

6 (54.5)

 
 

III

3 (15.0)

0 (0.0)

3 (27.3)

 

Pathological T (TNM system), n (%)

T0

9 (45.0)

9 (100.0)

0 (0.0)

 < 0.001

 

T2

3 (15.0)

0 (0.0)

3 (27.3)

 
 

T3

7 (35.0)

0 (0.0)

7 (63.6)

 
 

T4

1 (5.0)

0 (0.0)

1 (9.1)

 

Pathological N (TNM system), n (%)

N0

17 (85.0)

9 (100.0)

8 (72.7)

0.236

 

N1

2 (10.0)

0 (0.0)

2 (18.2)

 
 

N2

1 (5.0)

0 (0.0)

1 (9.1)

 

ypT_downstage, n (%)

Yes

10 (50.0)

8 (88.9)

2 (18.2)

0.001

 

No

7 (35.0)

0 (0.0)

7 (63.6)

 
 

Missing data

3 (15.0)

1 (11.1)

2 (18.2)

 

ypN_downstage, n (%)

Yes

11 (55.0)

6 (66.7)

5 (45.5)

0.552

 

No

7 (35.0)

2 (22.2)

5 (45.5)

 
 

Missing data

2 (10.0)

1 (11.1)

1 (9.1)

 
  1. P values for TR vs. PR.TR, total responders. PR, poor responders. nCRT, neoadjuvant chemoradiation therapy