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Table 3 Baseline comparison of blood routine and tumor biomarkers in different responses to nCRT from the internal discovery cohort

From: Identification of proteomic markers for prediction of the response to 5-Fluorouracil based neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

Laboratory index

TR

PR

p

Haemoglobin (g/L)

130.29 ± 17.67

133.30 ± 13.43

0.694

RBC (1012/L)

4.46 ± 0.46

4.52 ± 0.46

0.790

WBC (109/L)

5.80 ± 2.08

5.91 ± 2.00

0.907

Neutrophil

0.63 ± 0.07

0.62 ± 0.10

0.963

Lymphocyte

0.30 ± 0.07

0.28 ± 0.07

0.492

Monocyte

0.06 ± 0.014

0.06 ± 0.018

0.669

Eosinophil

0.01 ± 0.005

0.02 ± 0.017

0.169

Basophil

0.003 ± 0.002

0.004 ± 0.003

0.421

Platelet (109/L)

252 ± 58

200 ± 98

0.231

NLR

2.22 ± 0.77

2.48 ± 1.02

0.587

Fibrinogen (g/L)

3.38 ± 0.74

3.47 ± 0.47

0.764

CEA (μg/L)

5.50 ± 4.45

8.08 ± 8.61

0.519

AFP (μg/L)

3.17 ± 2.45

4.51 ± 3.55

0.445

CA125 (U/mL)

19.44 ± 13.49

11.46 ± 3.94

0.194

CA19-9 (U/mL)

43.35 ± 48.64

17.15 ± 19.78

0.184

  1. TR total responders, PR poor responders, RBC Red blood cell, WBC White blood cell, NLR Neutrophil/Lymphocyte, CEA carcinoembryonic antigen, AFP alpha-fetoprotein, CA125 Carbohydrate antigen 125, CA199 Carbohydrate antigen 19-9