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Table 1 Clinicopathological correlation of DAB2IP expression in ESCC

From: DAB2IP predicts treatment response and prognosis of ESCC patients and modulates its radiosensitivity through enhancing IR-induced activation of the ASK1-JNK pathway

DAB2IP expression

Variables

High

Low

P valuea

Age (years)

0.759

 ≤ 55b

22 (24.2%)

69 (75.8%)

 

 > 55

13 (26.5%)

36 (73.5%)

 

Sex

0.187

 Male

19 (21.3%)

70 (78.7%)

 

 Female

16 (31.4%)

35 (68.6%)

 

Location

0.399

 Cervical/upper thoracic

9 (31.0%)

20 (69.0%)

 

 Middle/lower thoracic

26 (23.4%)

85 (76.6%)

 

WHO grade

< 0.001

 G1

21 (61.8%)

13 (38.2%)

 

 G2

9 (12.3%)

64 (87.7%)

 

 G3

5 (15.2%)

28 (84.8%)

 

Tumor size (cm)

< 0.001

 ≤ 5c

23 (41.8%)

32 (58.2%)

 

 > 5

12 (14.1%)

73 (85.9%)

 

T status

0.003

 T2/3

11 (14.9%)

63 (85.1%)

 

 T4

24 (36.4%)

42 (63.6%)

 

N status

< 0.001

 N0

20 (62.5%)

12 (37.5%)

 

 N1

15 (13.9%)

93 (86.1%)

 

M status

0.017

 M0

27 (32.1%)

57 (67.9%)

 

 M1-lym

8 (14.3%)

48 (85.7%)

 

CRT response

< 0.001

 CR

18 (50.0%)

18 (50.0%)

 

 Non-CR

17 (16.3%)

87 (83.7%)

 

Locoregional progression

0.049

 Present

10 (16.7%)

50 (83.3%)

 

 Absent

25 (31.2%)

55 (68.8%)

 
  1. T tumor, N node, M metastases, CRT chemoradiotherapy, CR complete response, M1-lym distant lymph node metastasis, ESCC esophageal squamous cell carcinoma
  2. aChi-square test
  3. bMean age
  4. cMean tumor size