Cancer Cell International

Table 2 Predictive variables for OS and DSS of ESCC patients by log rank test

From: DAB2IP predicts treatment response and prognosis of ESCC patients and modulates its radiosensitivity through enhancing IR-induced activation of the ASK1-JNK pathway

Variables	OS (months)			DSS (months)
Variables	Case	Median	P	Case	Median	P^a
Age (years)			0.830			0.908
≤ 55^b	91	17.10		71	15.40
> 55	49	17.80		41	17.80
Gender			0.348			0.316
Male	89	17.80		69	16.70
Female	51	17.10		43	17.10
Location			0.353			0.385
Cervical/upper thoracic	29	18.03		24	17.80
Middle/lower thoracic	111	17.30		88	15.90
WHO grade			0.069			0.013
G1	34	21.40		26	22.40
G2	73	18.03		57	15.10
G3	33	15.70		29	15.50
Tumor size (cm)			0.004			0.003
≤ 5^c	55	27.10		41	28.40
> 5	85	14.77		71	14.60
T status			< 0.001			0.001
T2/3	74	26.80		64	22.60
T4	66	13.70		48	12.80
N status			0.043			0.028
N0	32	22.30		26	22.60
N1	108	16.90		86	15.10
M status			0.059			0.020
M0	84	19.90		63	19.30
M1-lym	56	15.40		49	14.80
CRT response			< 0.001			< 0.001
CR	36	36.90		31	36.90
Non-CR	104	14.60		81	13.90
DAB2IP expression			0.002			< 0.001
High	35	28.80		25	34.50
Low	105	15.90		87	14.77

OS overall survival, DSS disease specific survival
^aLog-rank test
^bMean age
^cMean tumor size

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