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Fig. 3 | Cancer Cell International

Fig. 3

From: BuFeiXiaoJiYin ameliorates the NLRP3 inflammation response and gut microbiota in mice with lung cancer companied with Qi-yin deficiency

Fig. 3

BFXJY treatment inhibited NLRP3 inflammasome activation in lung cancer with Qi-yin deficiency. A, B The relative mRNA expression of NLRP3 (A) and ASC (B) was determined using qRT-PCR. The data were expressed after being normalized to GAPDH. C–F The relative protein levels of NLRP3 (C and D), ASC (C and E), and pro-caspase-1 (C and F) were examined using western blot. The data were expressed after being normalized to GAPDH. G–J The distribution of NLRP3, ASC, and caspase-1 was also evaluated by IHC. The means ± SD of three independent samples were shown. Differences among multiple groups were analyzed by one-way analysis of variance and followed Duncan's test using the SPSS 20.0 package. *p < 0.05 compared to control group and #p < 0.05 compared to the Qi-yin deficiency + LPS-ATP group

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Cancer Cell International

ISSN: 1475-2867

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