Fig. 6
From: BMI1 promotes osteosarcoma proliferation and metastasis by repressing the transcription of SIK1
SIK1 functions as a tumor suppressor in OS cells. A Relative expression levels of SIK1 in OS cells transfected with si-NC or si-SIK1 1#, 2#, 3#, were tested by qRT-PCR. Sample size = 3. B CCK-8 assays were performed in OS cells transfected with si-NC or si-SIK1 1#, 2#. Sample size = 6. C Colony formation assays were used to determine the proliferative ability of OS cells transfected with si-NC or si-SIK1 1#, 2#. Sample size = 3. D Quantification of C. E Transwell assays in OS cells transfected with si-NC or si-SIK1 1#, 2#. Sample size = 3. F Quantification of E. **p < 0.01, ***p < 0.001, compared with si-NC