Fig. 6
From: RPL15 promotes hepatocellular carcinoma progression via regulation of RPs-MDM2-p53 signaling pathway
RPL15 silencing inhibited HCC cells migration and invasion. A Wound-healing assay indicated that RPL15 silencing reduced HCCLM3 cell migration while RPL15 overexpression enhanced Hep3B cell migration. B Transwell assay revealed that RPL15 knockdown decreased the invasion capability of HCCLM3 cells while overexpression of RPL15 in Hep3B cells demonstrated the opposite effect. C The expressions of EMT-related genes were detected after RPL15 was silenced or overexpressed in HCC cells via western blot. Data are presented as the mean ± SD, n = 3; *P < 0.05, compared to the control group