Fig. 8
From: RPL15 promotes hepatocellular carcinoma progression via regulation of RPs-MDM2-p53 signaling pathway
RPL15 mediated HCC progression via the RPs-MDM2-p53 signaling pathway. A The efficiency of p53 knockdown in HCCLM3 cells was confirmed by western blot. B CCK-8 assays showed that si-p53 reversed the inhibitory function of proliferation in HCCLM3 cell with RPL15 knockdown. C Wound-healing assay indicated that si-p53 reversed the inhibitory function of migration in HCCLM3 cell with RPL15 knockdown. D Transwell assay revealed that si-p53 reversed the inhibitory function of invasion in HCCLM3 cell with RPL15 knockdown. Data are presented as the mean ± SD, n = 3; *P < 0.05, compared to the control group; #P < 0.05, compared to the si-RPL15 group