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Fig. 2 | Cancer Cell International

Fig. 2

From: A synthesized olean-28,13β-lactam targets YTHDF1-GLS1 axis to induce ROS-dependent metabolic crisis and cell death in pancreatic adenocarcinoma

Fig. 2

B28 interrupts multiple crucial biological processes in PAAD. A PANC-1 cell were treated with or without B28 for 24 h, total RNA of cell samples were extracted and subjected to RNA-seq. Statistical analysis of variance in vehicle and B28 treated groups was plotted as volcano map. B Bioinformatics analysis combined with cluster analysis of gene transcription in vehicle and B28 treated cells. C Enrichment analysis of down-regulated and up-regulated differentially expressed genes (DEGs) based on KEGG database

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Cancer Cell International

ISSN: 1475-2867

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