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Table 2 Results of Annexin V/PI staining for cell apoptosis after HSV-HMGB1 1, and HSV-ble infection under normoxic or hypoxic condition

From: Cell type-specific response of colon cancer tumor cell lines to oncolytic HSV-1 virotherapy in hypoxia

CRC cells

Early Apoptotic (%)

Late Apoptotic/Necrotic (%)

Total Apoptotic (%)

HCT116 HSV-HMGB1

19.29

54.33

73.62

HCT116 HSV-ble

10.49

19.04

29.53

HCT116 HSV-HMGB1 Hypoxia

13.05

49.18

62.23

HCT116 HSV-ble Hypoxia

9.18

26.75

35.93

HT29 HSV-HMGB1

14.73

20.66

35.39

HT29 HSV-ble

10.77

20.38

31.15

HT29 HSV-HMGB1 Hypoxia

8.56

10.74

19.3

HT29 HSV-ble Hypoxia

5.84

15.15

20.99

SW480 HSV-HMGB1

5.11

22.68

27.79

SW480 HSV-ble

2.26

21.51

23.77

SW480 HSV-HMGB1 Hypoxia

4.18

12.75

16.93

SW480 HSV-ble Hypoxia

3.69

4.44

8.13