Fig. 3

MiR-146a promoted HepG2 cell proliferation, cycle progression, migration and invasion. a miR-146a transcript levels of HepG2 cells transfected with control (LV-vector) or Lentivirus packaged miR-146a overexpression vector (LV-miR-146a). b FLAP protein and transcript levels of HepG2 cells transfected with control (LV-vector) or Lentivirus packaged miR-146a overexpression vector (LV-miR-146a). c Representative CCK-8 proliferation assays (left) and the cell cycle regulatory proteins expression in HepG2 cells. d Flow cytometry analysis (left) and quantitation (right) in HepG2 cells. e Representative wound-healing scratch assays (left) and quantitation (right) in HepG2 cells. f Representative matrigel invasion assay (left) and adhesion markers expression (right) in HepG2 cells. Data are presented as mean ± SEM. n = 3; **P < 0.01, ***P < 0.001,****P < 0.0001