Fig. 5

High FLAP expression inhibited HepG2 cell proliferation, cycle progression, migration and invasion. a FLAP protein and transcript levels of HepG2 cells transfected with control (LV-vector) or Lentivirus packaged FLAP overexpression vector (LV-FLAP). b Representative CCK-8 proliferation assays (left) and the cell cycle regulatory proteins expression in HepG2 cells. c Flow cytometry analysis (left) and quantitation (right) in HepG2 cells. d Representative wound-healing scratch assays (left) and quantitation (right) in HepG2 cells. e Representative matrigel invasion assay (left) and adhesion markers expression (right) in HepG2 cells. Data are presented as mean ± SEM. n = 3; *P < 0.05, ***P < 0.001,****P < 0.0001