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Fig. 4 | Cancer Cell International

Fig. 4

From: Exosomal miR-301a-3p from esophageal squamous cell carcinoma cells promotes angiogenesis by inducing M2 polarization of macrophages via the PTEN/PI3K/AKT signaling pathway

Fig. 4

ESCC cell-derived exosomes promote angiogenesis by inducing M2 polarization of macrophages. a Proliferation activity of TECs was detected using the CCK-8 assay. b–e Migration ability, invasion ability, and tube formation ability of TECs co-cultured with the supernatant of macrophages incubated with ESCC cell-derived exosomes were detected using the scratch assay and Transwell migration assay (b, c), Transwell invasion assay (d), and tube formation assay (e), respectively. *p < 0.05, **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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