Fig. 6

Analysis of the association between mRNA expression level of AACT and overall survival in tumors. A, B The fragment per kilobase of exon model per million mapped reads (FPKM) data of AACT mRNA expression levels were downloaded from the Human Protein Atlas database (https://www.proteinatlas.org/ENSG00000196136-SERPINA3) (Additional file 1), and overall survival analysis was performed using the Kaplan–Meier method, followed by the log-rank test with SPSS 24.0 software. The FPKM cutoff of AACT mRNA expression in liver cancer was 1.41 (A) and in pancreatic cancer was 0.9 (B). C, D The overall survival analysis was performed using the Kaplan–Meier Plotter database (http://www.kmplot.com/analysis/index.php?p=service&cancer=lung). The parameter settings: Affy ID: 232376_at; Split patients by: Auto select best cutoff; Survival: OS; History: all; grade: all; Gender: all; Smoking history: all; Cox regression: univariate. C. In early-stage lung cancer. Stage: 1; AJCC stage T: 1; AJCC Stage N: 0; AJCC stage M: 0. D. In lung cancer. Stage: all; AJCC stage T: all; AJCC Stage N: all; AJCC stage M: all