Fig. 2
From: PICALM exerts a role in promoting CRC progression through ERK/MAPK signaling pathway
PICALM is required for CRC cell proliferation and apoptosis. A The effect of knockdown or overexpression of PICALM on HCT 116 and RKO cells proliferation was examined by cell counting experiment. B Flow cytometry analysis based on Annexin V-APC staining was utilized to detect the percentage of early apoptotic cell for HCT 116 and RKO cells. The representative images were selected from at least 3 independent experiments. The data was presented as the mean ± SD (n = 3). **P < 0.01, ***P < 0.001