Fig. 4
From: PICALM exerts a role in promoting CRC progression through ERK/MAPK signaling pathway
Knockdown of PICALM inhibits tumor growth in mice xenograft models. A The fluorescence intensity of tumors in the shCtrl group and shPICALM group was demonstrated. B The volume of tumors in shCtrl group and shPICALM group was measured after post-injection. C The average weight of tumors in shCtrl group and shPICALM group was measured. D Images of mice and tumors in shCtrl group and shPICALM group. E Tumor tissues in shCtrl group and shPICALM group were examined for Ki67 staining by IHC. The data was presented as the mean ± SD (n = 3). *P < 0.05