Fig. 4

RIP-Seq analysis reveals CEBPB as a direct target of EIF3B. A RIP-Seq and proteome analyses reveal 8 genes that showed significant differential expression at the protein level (B) and direct mRNA binding affinity by EIF3B. C Significantly deregulated mRNAs were used for ENCODE and ChEA consensus transcription factor prediction, and the top 20 transcription factors are shown. Based on the RIP-Seq, proteome and RNA-seq results, the transcription factor CEBPB was proposed as a direct target of EIF3B. The binding motif and peaks of EIF3B with CEBPB mRNA are shown in D