Table 1 Univariate and multivariate Cox proportional hazards regression analyses for PFS of LRRN4 and clinical features
From: Prognostic value and biological function of LRRN4 in colorectal cancer
Variables | Univariable Cox | Multivariable Cox | ||||
|---|---|---|---|---|---|---|
HR | 95%CI | p value | HR | 95%CI | p value | |
LRRN4 (high vs. low) | 1.992 | 1.143–3.469 | 0.015 | 1.797 | 1.009–3.200 | 0.047 |
MSI (high vs. low) | 0.677 | 0.316–1.448 | 0.314 | 1.209 | 0.524–2.792 | 0.656 |
Age | 1.346 | 0.753–2.407 | 0.316 | 1.020 | 0.997–1.044 | 0.092 |
Gender (male vs. female) | 1.348 | 0.772–2.354 | 0.294 | 1.118 | 0.619–2.020 | 0.712 |
Histological type (nonmucinous vs. mucinous) | 0.394 | 0.121–1.278 | 0.121 | 0.425 | 0.128–1.410 | 0.162 |
Pathologic stage (III/IV vs. I/II) | 2.900 | 1.620–5.192 | 0.000 | 1.707 | 0.814–3.578 | 0.157 |
Lymphatic invasion (yes vs. no) | 2.348 | 1.346–4.095 | 0.003 | 1.067 | 0.423–2.690 | 0.890 |
Perineural invasion (yes vs. no) | 1.932 | 1.093–3.418 | 0.024 | 1.268 | 0.637–2.522 | 0.499 |
Venous invasion (yes vs. no) | 2.045 | 1.170–3.575 | 0.012 | 1.215 | 0.523–2.824 | 0.650 |
Adjuvant chemoradiotherapy (no vs. yes) | 3.540 | 1.184–6.652 | 0.000 | 2.781 | 1.289–6.000 | 0.009 |