Table 2 Univariate and multivariate Cox proportional hazards regression analyses for OS of LRRN4 and clinical features
From: Prognostic value and biological function of LRRN4 in colorectal cancer
Variables | Univariable Cox | Multivariable Cox | ||||
|---|---|---|---|---|---|---|
HR | 95%CI | p value | HR | 95%CI | p value | |
LRRN4 (high vs. low) | 2.063 | 1.247–3.413 | 0.005 | 1.733 | 1.014–2.961 | 0.044 |
MSI (high vs. low) | 0.913 | 0.463–1.801 | 0.792 | 0.957 | 0.449–2.039 | 0.909 |
Age | 1.032 | 1.011–1.053 | 0.002 | 1.035 | 1.012–1.059 | 0.003 |
Gender (male vs. female) | 1.667 | 0.993–2.798 | 0.053 | 1.541 | 0.898–2.644 | 0.116 |
Histological type (mucinous vs. nonmucinous) | 1.239 | 0.588–2.611 | 0.573 | 1.254 | 0.570–2.760 | 0.574 |
Pathologic stage (III/IV vs. I/II) | 2.914 | 1.723–4.927 | 0.000 | 4.691 | 2.333–9.431 | 0.000 |
Lymphatic invasion (yes vs. no) | 2.025 | 1.214–3.377 | 0.007 | 0.633 | 0.268–1.496 | 0.298 |
Veno ius invasion (no vs. yes) | 0.990 | 0.597–1.640 | 0.968 | 2.180 | 0.949–5.005 | 0.066 |
Adjuvant chemoradiotherapy (no vs. yes) | 2.481 | 1.487–4.138 | 0.001 | 0.540 | 0.291–1.001 | 0.051 |