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Table 2 Eleven of 232 DEGs enriched in cancer metastasis-related GO processe (regulation of cell adhesion, GO:0,045,785)

From: Tetraspanin 7 promotes osteosarcoma cell invasion and metastasis by inducing EMT and activating the FAK-Src-Ras-ERK1/2 signaling pathway

Gene names

Expression value

− shTspan7#1

Expression value

− shTspan7#2

Expression value

− shNC#1

Expression value

− shNC#2

Log2 fold change

p-value

SIRPB1

1.118376464

0.495721813

0.80962826

2.165084088

− 3.227314657

p < 0.05

PIK3R6

0.340225214

0.62066055

0.633537001

1.715767173

− 3.126669927

p < 0.05

HAS2

0.817346468

0.319630554

1.6547263

1.258389977

− 2.885789675

p < 0.05

FN1

3.418682032

3.319196043

3.551829513

4.296320867

− 2.310111273

p < 0.05

TPM1

3.368796466

3.628408328

4.124010519

3.896079796

− 1.684664957

p < 0.05

FERMT1

1.852108575

2.167819671

2.658842866

2.107604583

− 1.423064871

p < 0.05

IL7R

2.887999919

3.038961841

3.468381406

3.193897243

− 1.271159105

p < 0.05

IGF2

2.672663674

2.782776691

2.829436653

3.270101357

− 1.234961466

p < 0.05

S100A10

3.747871011

3.777285409

3.901958948

4.228364707

− 1.103723422

p < 0.05

PODXL

3.892223833

3.599639507

3.739103952

4.266308368

− 1.023388653

p < 0.05

SDC4

3.623752579

3.443318896

3.570804073

4.017503585

− 1.017531903

p < 0.05

  1. The significance of row given in bold in the table is to hightlight the direction of research