Fig. 4
From: DNA repair and damage pathways in mesothelioma development and therapy
The association between mutations in DDR components and MMe development after DNA damage. XRCC1, MSH6, MLH1, KU70/80, and BAP1 are frequently mutated among BER, MMR, NHEJ, and HR repair pathways, leading to MMe development. MMe Malignant mesothelioma, BER base excision repair, MMR miss match repair, NHEJ nonhomologous end-joining repair, HR homologs recombination