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Fig. 7 | Cancer Cell International

Fig. 7

From: Decreased INPP5B expression predicts poor prognosis in lung adenocarcinoma

Fig. 7

Validation of overexpressed INPP5B as a tumor suppressor in vitro. a The CCK-8 assay showed the overexpression of INPP5B inhibited proliferation of lung adenocarcinoma cells. b The colony formation assay showed INPP5B overexpression suppressed the proliferation abilities of lung adenocarcinoma cells. c Cell cycle and statistical analysis showed significant G2 arrest after INPP5B overexpression. d Results of wound healing assay showed that INPP5B overexpression inhibited the migration ability of lung adenocarcinoma cells. Scale bar: 50 μm. e Results of transwell assay showed significant decrease in the migration ability of lung adenocarcinoma cells after INPP5B overexpression. Scale bar: 50 μm. *p < 0.05, **p < 0.01, ***p < 0.001

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