Fig. 6

The combination of G-CSF and ATO inhibited the tumor growth of AML cells in vivo. A The scheme for the establishment of the xenograft mouse model and drug treatment. B The tumor growth curves of the indicated groups. C, D The mice were euthanized on Day 17 after treatment, and the tumors were separated and weighted. E Immunohistochemistry with anti-CEBPB and anti-AQP9 antibodies for the tumor sections from the indicated groups. F The HE staining of liver sections from the indicated groups. G The hypothetical mechanism of the combinational effect of G-CSF and ATO