Fig. 4
From: Mechanisms of miR-3189-3p-mediated inhibition of c-MYC translation in triple negative breast cancer
miR-3189-3p mediates c-MYC downregulation at translational level. A Expression of c-MYC mRNA in different subtypes of breast cancer (METABRIC). * Indicates statistical significance. B Western blot for c-MYC protein from MDA-MB-231 cells transfected with miR-3189-3p (miR) or scramble control (Ctrl) for 72 h. Densitometric analysis of the bands relative to c-MYC was done using Image J. C Western blots performed on MDA-MB-231 cells that were transfected with scramble control (Ctrl) or miR-3189-3p (miR) in the absence or presence of the proteasome inhibitor MG132. 14–3-3 was used as loading control