Fig. 5
From: Mechanisms of miR-3189-3p-mediated inhibition of c-MYC translation in triple negative breast cancer
Overexpression of miR-3189-3p downregulates c-MYC and 4EBP1 protein levels in TNBC cells but not in normal epithelial cells. A Western blot to detect 4EBP1 and eIF4E proteins in MDA-MB-231 cells transfected with miR-3189-3p (miR) or scramble control (Ctrl). B, C Representative Western blots showing expression of c-MYC, 4EBP1, and eIF4E in MDA-MB-468 (b) and HME1 normal epithelial cells. GAPDH was used as loading control