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Fig. 2 | Cancer Cell International

Fig. 2

From: STAT3-mediated upregulation of LINC00520 contributed to temozolomide chemoresistance in glioblastoma by interacting with RNA-binding protein LIN28B

Fig. 2

Overexpression of LINC00520 contributed to TMZ chemoresistance of GBM cells. A The efficiency of LINC00520 overexpression in U251 and SKMG-1 cells was detected by qRT-PCR analysis. B The viability of GBM cells treated with TMZ was significantly increased by LINC00520 overexpression. C LINC00520 overexpression promoted colony formation of U251 and SKMG-1 cells treated with 200 µM TMZ. The effect of LINC00520 overexpression on cell apoptosis of GBM was analyzed by flow cytometry (D) and TUNEL assay (E), respectively. F LINC00520 overexpression elevated the proportion of G1 phase in U251 and SKMG-1 cells treated with 200 µM TMZ

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Cancer Cell International

ISSN: 1475-2867

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