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Fig. 3 | Cancer Cell International

Fig. 3

From: STAT3-mediated upregulation of LINC00520 contributed to temozolomide chemoresistance in glioblastoma by interacting with RNA-binding protein LIN28B

Fig. 3

STAT3 promoted the transcription of LINC00520 via binding to its promoter. A Luciferase reporter assays revealed that LINC00520 expression in TMZ-sensitive and TMZ-resistant cells could be regulated by transcription factor STAT3. B ChIP assay further supported that STAT3 was a key regulator of LINC00520 transcription (PCR 1 was conducted using the specific primer for LINC00520, and PCR 2 was conducted using the control primer)

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Cancer Cell International

ISSN: 1475-2867

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