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Fig. 5 | Cancer Cell International

Fig. 5

From: STAT3-mediated upregulation of LINC00520 contributed to temozolomide chemoresistance in glioblastoma by interacting with RNA-binding protein LIN28B

Fig. 5

LIN28B contributed to TMZ chemoresistance by inhibiting cell autophagy and reducing DNA-damage response. A The effects of LINC00520/LIN28B axis on cell autophagy of GBM were measured by immunofluorescence labeled with GFP-LC3. B The expression of autophagy-related proteins, including LC3II, LC3I and Beclin-1, were detected by Western blot. C The alkaline comet assay indicated that LINC00520/LIN28B axis contributed to TMZ chemoresistance in GBM via reducing DNA damage response

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Cancer Cell International

ISSN: 1475-2867

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