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Table 1 Established function of myricetin in different cancer cell lines

From: Myricetin: targeting signaling networks in cancer and its implication in chemotherapy

Cell lines/in vitro

Tumor type

Effect of Myricetin

Reference

DU145

PC3

Prostate Cancer

↓ metastasis,

↓epithelial-mesenchymal transition

↓invasiveness, ↑apoptosis

[118]

HCT-15

HT-29

Colon cancer

↑apoptosis

↓inhibits proliferation in a dose-dependent manner

[45, 52]

HepG2

A549

H1299

Hepatocellular Carcinoma

↑growth arrest, ↑ autophagy

↑growth arrest

↓proliferation

[54, 123, 124]

HGC-27

SGC7901

Gastric Cancer

↓ proliferation

↓growth

↑apoptosis in a dose-dependent manner

[20]

KYSE30

EC9706

Esophageal Carcinoma

↓proliferation, ↑apoptosis, ↓migration

↓invasion of tumor cells in a dose-dependent manner

[119]

MCF-7

MDA-Mb-231

Breast Cancer Cells

↑ apoptosis, ↓metastasis, ↓migration, ↓invasion

[36, 46]

OVCAR-3

A2780/CP70

SKOV3

Ovarian Cancer

↑ apoptosis

↓cells migration

↓angiogenesis

[125]

Panc1

S2-013

PaCa-2

Pancreatic Cancer

↑apoptosis

[75]

T24

Bladder Cancer

↑ growth arrest at M-phase,

↑apoptosis, ↓proliferation, ↓cell migration

[105]

  1. Symbols: ↑ increase, ↓ decrease