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Fig. 1 | Cancer Cell International

Fig. 1

From: Nectin-4 promotes osteosarcoma progression and metastasis through activating PI3K/AKT/NF-κB signaling by down-regulation of miR-520c-3p

Fig. 1

The Nectin‑4 expression and clinical significance in OS. A The expression of Nectin-4 in OS (n = 29) and adjacent normal tissues (n = 8) by using RT-qPCR analysis. B, C The expression of Nectin-4 in the 8 paired samples of OS and adjacent normal tissues at mRNA and protein levels. D Immunohistochemical (IHC) stain analysis of Nectin-4 expression in OS specimens and normal tissues on tissue microarrays (scale bars 100 μm, magnifications of 200×). E, F The basal expression levels of Nectin-4 in OS cell lines (MG63, U2OS, and 143B) and osteoblastic cell line (hFOB1.19) by using RT-qPCR and Western blotting. Each assay was repeated at least three times. ns, no significance; *P < 0.05; **P < 0.01; ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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