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Table 1 Association between Nectin-4 expression and clinicopathologic features in GSE21257

From: Nectin-4 promotes osteosarcoma progression and metastasis through activating PI3K/AKT/NF-κB signaling by down-regulation of miR-520c-3p

Variable

 

No

Nectin-4 expression

x2

P-value

High

Low

Gender

    

0.235

0.625

Male

34

13 (24.53%)

21 (39.62%)

  

Female

19

6 (11.32%)

13 (24.53%)

  

Age

    

0.051

0.821

 ≥ 18.7Y

13

5 (9.43%)

8 (15.09%)

  

 < 18.7Y

40

14 (26.42%)

26 (49.06%)

  

Grade

    

8.958

0.176

1

13

7 (13.21%)

6 (11.32%)

  

2

16

5 (9.43%)

11 (20.75%)

  

3

13

2 (3.77%)

11 (20.75%)

  

4

5

3 (5.66%)

2 (3.77%)

  

Metastasis

    

5.182

0.036*

Yes

34

16 (30.19%)

18 (33.96%)

  

No

19

3 (5.66%)

16 (30.19%)

  
  1. Using Chi-square test or Fisher’s exact test
  2. *P < 0.05 was considered statistically significant