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Fig. 2 | Cancer Cell International

Fig. 2

From: Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer

Fig. 2

A schematic illustration of the mechanisms of hormonal modulation of telomerase in cancer cells. Accumulating findings have detected that androgen receptor, estrogen receptor, and progesterone receptor can play a crucial role in the regulation of hTERT expression in tumor cells. In addition, stress hormones can lead to overexpression of cellular telomerase activity in response to various environmental stimuli [159]

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Cancer Cell International

ISSN: 1475-2867

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