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Fig. 1 | Cancer Cell International

Fig. 1

From: TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma

Fig. 1

TRIM36 expression is downregulated in HCC and correlates with poor clinical outcomes. a Western blotting analysis of TRIM36 expression in HCC and adjacent non-tumor tissues. N = adjacent non-tumor tissues, T = HCC tissues. b Graph showing TRIM36 expression in HCC and adjacent non-tumor tissues, p value was calculated using two-tailed paired Student’s t-test, n = 20 independent repeats. c Violin plot graph showing the immunohistochemistry staining scores of TRIM36 in HCC and adjacent non-tumor tissues. P value was calculated using two-tailed paired Student’s t-test, n = 92 independent repeats. d Immunohistochemistry image showing the expression of TRIM36 in HCC and adjacent non-tumor tissues. Scale bars, 100 μm. e Kaplan–Meier analysis of TRIM36 (NTRIM36-high = NTRIM36>4 = 37, NTRIM36-low = NTRIM36≤4 = 55) for overall survival (OS). f Kaplan–Meier analysis of TRIM36 (NTRIM36-high = NTRIM36>4 = 37, NTRIM36-low = NTRIM36≤4 = 55) for recurrence-free survival (RFS). g-h Univariate and multivariate Cox analysis of OS. ***P < 0.001

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