Fig. 2
From: Apoptosis evasion via long non-coding RNAs in colorectal cancer
Summarized scheme with mechanisms of apoptosis evasion in colorectal cancer. Symbols: ↓down-regulation, ↑ up-regulation. Abbreviations and symbols: ↑ (increase), ↓ (decrease), Bcl-2 (B-cell lymphoma 2), Bcl-XL (B-cell lymphoma-extra large), Bax (BCL2 Associated X, Apoptosis Regulator), Bim (B cell lymphoma-2-like 11), MCL-1 (Myeloid cell leukemia-1), \XIAP (X-linked inhibitor of apoptosis protein), CIAP (cellular inhibitor of apoptosis), PUMA (p53 upregulated modulator of apoptosis), COX-2 (cyclo-oxygenase-2), PGE2 ( Prostaglandin E2)