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Table 3 Selected factors according to the Cox PHs regression model based on the training and validation cohorts

From: Prognostic value of the modified systemic inflammation score in non-small-cell lung cancer with brain metastasis

Characteristics

Training set

Validation set

HR (95% CI)

P value

HR (95% CI)

P value

Receiving local treatment (Surgery/WBRT/SRS)

 Yes

1

 

1

 

 No

1.769(1.471–2.127)

 < 0.001

1.806(1.504–2.169)

 < 0.001

Receiving chemotherapy

 Yes

1

 

1

 

 No

1.313(1.082–1.618)

0.006

1.318(1.078–1.612)

0.007

NLR

  ≥ 4.71

1

 

1

 

  < 4.71

0.630(0.517–0.767)

 < 0.001

0.634(0.521–0.772)

 < 0.001

Albumin

  < 40 mg/l

1

 

1

 

  ≥ 40 mg/l

0.617(0.514–0.741)

 < 0.001

0.610(0.508–0.732)

 < 0.001

  1. WBRT, whole-brain radiation therapy; SRS, stereotactic radiosurgery; NLR, neutrophil–lymphocyte ratio