Table 4 Function of miR-1908 in non-malignant conditions based on studies in animal models (SD: Sprague–Dawley)
From: miR-1908: a microRNA with diverse functions in cancers and non-malignant conditions
Disease Type | Animal models | Results | References |
|---|---|---|---|
Myocardial infarction | 8–10-week-old male SD rats | miR-1908 expression was reduced at 4 weeks after myocardial infarction ↑↑ miR-1908: ↓ myocardial fibrosis, and TGF-β1 and Smad2/3 levels | [16] |
Renal fibrosis | renal fibrosis mouse models | ↑↑ miR-1908: ↓ renal fibrosis | [19] |
Scar formation post-burn wound healing | male SD rats | ↑↑ miR-1908: ↑ scar formation | [21] |