Table 6 Dysregulation of miR-1908 in clinical samples from non-malignant conditions (UP: unipolar disorder, BP: bipolar disorder)
From: miR-1908: a microRNA with diverse functions in cancers and non-malignant conditions
Disease type | Samples | Expression (Disease vs. Normal) | References |
|---|---|---|---|
Bipolar disorders | 17 UP and 15 BP patients | Down in bipolar disorder patients in comparison to remission phase | [26] |
Ischemic stroke | 13 normal control subjects (NCs), 23 cardioembolism (CARD), 26 cases of large artery atherosclerosis (LAA), 27 cases of lacunar infarct (LAC), and 11 cases of stroke of undetermined etiology (SUE) 20 NCs, 28 CARD, 23 LAA, 18 LAC, and 16 SUE | Down in LAA, LAC, and SUE patients but not in CARD patients | [27] |
Obesity | 16 human adipose tissues of obese cases and 12 matched normal tissues | Down in subcutaneous, up in visceral tissues of obese patients | [17] |
Scar formation post-burn wound healing | Wound tissue and adjacent normal dermal Tissues from 46 patients with deep second-degree burns and hypertrophic scarring | Up in burn-wounded skin compared with adjacent normal skin, down when the wound was healing and then increased during scar development | [21] |