Fig. 1From: Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technologyGraphical representation showing the formation of siRNA loaded PLGA-PVA NPs and autophagy in PC9GR cells. After the fabrication of siRNA loaded PLGA-PVA NPs, they enter into PC9GR cells with the coordination of US, and then suppress the expression of PDLIM5 gene and therefore induces autophagy which leads to the increase of autophagosomes. NPs, nanoparticles; US, ultrasoundBack to article page