Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology

Fig. 2

Bioinformatic analysis of PDLIM5. A The expression distribution of PDLIM5 in non-small cell lung cancer (NSCLC) tissues (Red colour: G1 group) and normal tissues (Blue colour: Normal group). The abscissa represents the different groups of samples, and the ordinate represents the expression distribution of the gene. *Represents the significant P values, ****P < 0.001. The statistical difference between the two groups was compared using the Wilcox test. B Overall survival probability in different groups with a high or low expression of PDLIM5. Red: high PDLIM5 expression, Blue: low PDLIM5 expression. Kaplan–Meier survival analysis of the gene signature from The Cancer Genome Atlas dataset and different groups were compared using a log-rank test. Hazard Ratio (HR) (High exp) represents the HR of the low-expression sample compared to the high-expression sample. HR > 1 indicates a risk factor. The median survival time (LT50) for the high and low expression groups are 3.7 and 4.6 years, respectively

Back to article page