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Fig. 7 | Cancer Cell International

Fig. 7

From: Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology

Fig. 7

The cytotoxicity of NBs and US sensitive siRNA-NBs in PC9GR cells was determined using a CCK-8 assay. As shown in Fig. 5A, the control, NB and siRNA -NB groups showed no obvious cytotoxicity, and the cell viability rate was above 95%. In Fig. 5B, there was no significant difference in cell viability rate among the three groups when the concentration varied from 0.1 to 2.0 ug/ml (P > 0.05). However, compared with the control group, the cell viabilities of the NB and siRNA-NBs groups were significantly reduced (P < 0. 05) up to 5 ug/ml, but they remained more than 75% viable

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Cancer Cell International

ISSN: 1475-2867

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