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Table 2 Demographic and clinicopathological characteristics of patients

From: CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross-sectional study with a systematic review

Parameters

PTC

FTC

MNG

Total

Patients number

28

9

27

64

Gender

 Male

2 (7.1)

4 (50)

8 (29.6)

14 (22.2)

 Female

26 (92.9)

4 (50)

19 (70.4)

49 (77.8)

Age (years)

 < 45

21 (75)

3 (37.5)

8 (29.6)

32 (50.8)

 ≥ 45

7 (25)

5 (62.5)

19 (70.4)

31 (49.2)

BRAF V600E mutation

 Positive

12 (46.2)

2 (22.2)

–

–

 Negative

14 (53.8)

7 (77.8)

–

–

Tumor size (cm)

 < 2

13 (46.4)

2 (25)

–

–

 ≥ 2

15 (53.6)

6 (75)

–

–

Extrathyroidal extension

 Positive

4 (14.8)

3 (42.9)

–

–

 Negative

23 (85.2)

4 (57.1)

–

–

Extracapsular invasion

 Positive

4 (14.8)

3 (42.9)

–

–

 Negative

23 (85.2)

4 (57.1)

–

–

Lymph node metastasis

 Positive

8 (29.6)

1 (14.3)

–

–

 Negative

19 (70.4)

6 (85.7)

–

–

Blood vascular invasion

 Positive

4 (14.8)

2 (71.4)

  

 Negative

23 (85.2)

5 (28.6)

  

TNM stage (AJCC)

 I and II

23 (82.1)

4 (57.1)

–

–

 III and IV

5 (17.9)

3 (42.9)

–

–

  1. PTC papillary thyroid cancer, FTC follicular thyroid cancer, MNG multinodular goiter, AJCC American Joint Committee on Cancer