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Fig. 8 | Cancer Cell International

Fig. 8

From: STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment

Fig. 8

The correlation of survival-related IRCGS and immune cell infiltrates in HCC. A–C The stromal, immune, and ESTIMATE scores were calculated across the high and low expression of VAV1, RHOA, and ZC3HAV1 in HCC cohorts from TCGA and ICGC databases. D–F The fractional difference in the infiltration of 22 immune cell subtypes between low and high expression of VAV1, RHOA, and ZC3HAV1 from the TCGA HCC cohort was evaluated via CIBERSORT algorithm. G The correlation of key IRCGS and the distribution of immune cell subtypes was further determined in three separate single-cell sequencing HCC datasets from TISCH database. TISCH: Tumor Immune Single-cell Hub. All *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns: no significance

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Cancer Cell International

ISSN: 1475-2867

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