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Fig. 4 | Cancer Cell International

Fig. 4

From: Characterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer

Fig. 4

TME immune cell infiltration and transcriptome characterization in three P-CA clusters. A Assessing the abundance of infiltrated immune cells among three distinct P-CA clusters. *p < 0.05, **p < 0.01, ***p < 0.001, ns, non-significant, and p-value < 0.05 was considered statistically significant. B Scatter plot of transcriptome features via Principal component analysis. C Venn plots show the number of unique and shared DEGs from different comparisons among three P-CA clusters. D GO enrichment analysis of the overlapping DEGs among distinct P-CA clusters. The length and color depth of the bar stands for the number of genes enriched and the q-value of each GO term, respectively. E KEGG pathway enrichment analysis of overlapping genes. TME, tumor microenvironment; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes

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