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Fig. 5 | Cancer Cell International

Fig. 5

From: Characterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer

Fig. 5

Feature selection and signature construction process. A Heatmap for the relationship of clinicopathologic characteristics with P-CA gene clusters. B Kaplan-Meier survival curves reveal the significant difference in prognosis advantage among three distinct P-CA gene clusters (log-rank tests, p-value < 0.001). C The difference in the expression of P-CA-related genes among three distinct P-CA gene clusters. D Alluvial diagram showing the relations of P-CA cluster, gene cluster, risk group, and status. E Kaplan–Meier curves revealed that the P-CA score was markedly related to the overall survival of patients with gastric cancer (log-rank tests, p-value < 0.001). F Correlation between P-CA score and multiple immune infiltrating cells. A negative correlation is marked with blue and a positive correlation is marked with red. * was considered statistically significant. G Differential expression analysis of the P-CA score in the P-CA cluster. H Difference analysis of the P-CA score in the gene cluster

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Cancer Cell International

ISSN: 1475-2867

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