Fig. 2
From: Strategies to overcome the main challenges of the use of exosomes as drug carrier for cancer therapy
Biogenesis of exosomes shows the role of endosome in exosome formation from early endosome by invagination to late endosome and multivesicular bodies (MVBs) that contain intraluminal vesicles (ILVs). On the other hand, it shows the action of Rab5, other proteins, and molecules in exosome formation and its transport to fuse with the cell membrane and eventually release exosomes from the parent cell to the target cell